Fructose and the Liver

Some recent science helps us better understand why consuming a lot of sugar (50:50 fructose+glucose) is not good for us.

While glucose is able to be absorbed directly by nearly all body tissue, fructose needs to be first converted and the highlighted study shows that fructose is processed by the small-intestines and converted into glucose.  However, the small-intestines are adapted to only receive small doses of fructose and any excess is shunted to the liver where it is largely converted to fat.

While further experiments need to be conducted, it appears that the human small-intestine may max out with less than 5 grams of fructose.

In mice, fructose gets processed in the small intestine before getting to the liver.


Sugar industry withheld evidence of sucrose’s health effects nearly 50 years ago

A U.S. sugar industry trade group appears to have pulled the plug on a study that was producing animal evidence linking sucrose to disease nearly 50 years ago, researchers argue in a paper publishing on November 21 in the open access journal PLOS Biology.